To host .net core in IIS:

1. install runtime-aspnetcore-7.0.<lastet>-windows-hosting-bundle-installer
2. create new apppool (only 1 app per pool), set apppool to "No managed code"
3. Extract zip of installation into your site folder
4. Change the web.config:

<aspNetCore processPath=".\AppCompleteGenericCore.exe" stdoutLogEnabled="false" stdoutLogFile=".\logs\stdout" hostingModel="inprocess" arguments="-iis=https://localhost/mdrCore1" />  SET THE URL YOUR APP SHOULD USE

Complete web.config

<?xml version="1.0" encoding="utf-8"?>
<configuration>
  <location path="." inheritInChildApplications="false">
    <system.webServer>
      <handlers>
        <add name="aspNetCore" path="*" verb="*" modules="AspNetCoreModuleV2" resourceType="Unspecified" />
      </handlers>
      <aspNetCore processPath=".\AppCompleteGenericCore.exe" stdoutLogEnabled="false" stdoutLogFile=".\logs\stdout" hostingModel="inprocess" arguments="-iis=https://localhost/MDRDebug"  />
    </system.webServer>
  </location>
</configuration>
<!--ProjectGuid: 3F248237-FF1B-4F4B-9029-DB6440643978-->

When you want to debug from VS - set argument -iis=https://localhost/mdrcore1/ or the name you have , stop apppool, compile, then start apppool and app - navigate via browser

Turnkey core in IIS

The turnkey core can also be hosted in IIS. In its Web.config point out its target url just like for MDrivenServer Core. Also add a MDrivenServerOverride.xml file in its App_Data so that the your mdrivenserver may be found.