To host .net core in IIS:

1. install runtime-aspnetcore-7.0.<lastet>-windows-hosting-bundle-installer
2. create new apppool (only 1 app per pool), set apppool to "No managed code"
3. Extract zip of installation into your site folder
4. Change the web.config:

<aspNetCore processPath=".\AppCompleteGenericCore.exe" stdoutLogEnabled="false" stdoutLogFile=".\logs\stdout" hostingModel="inprocess" arguments="-iis=https://localhost/mdrCore1" />  SET THE URL YOUR APP SHOULD USE

Complete web.config

When you want to debug from VS - set argument -iis=https://localhost/mdrcore1/ or the name you have , stop apppool, compile, then start apppool and app - navigate via browser